

🐕✨ Calm the itch, flaunt the shine — because your pet deserves the best!
Douxo S3 Calm Shampoo features 0.75% Ophytrium, a vet-recommended soothing ingredient clinically proven to relieve itching and inflammation caused by allergies in dogs and cats. This hypoallergenic formula not only calms irritated skin within 7 days but also repairs the skin ecosystem while detangling and enhancing coat softness and shine. Safe for all life stages and ideal for long-term use, it’s the go-to solution for pets with sensitive, allergic skin.





| ASIN | B09478KGJZ |
| ASIN | B09478KGJZ |
| Age Range Description | All Life Stages |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #1,521 in Pet Supplies ( See Top 100 in Pet Supplies ) #14 in Dog Shampoos |
| Brand Name | Douxo |
| Color | Translucent |
| Customer Reviews | 4.6 4.6 out of 5 stars (3,493) |
| Date First Available | May 5, 2021 |
| Date First Available | May 5, 2021 |
| Directions | Use as recommended by your veterinarian. Wet the fur with cool water from the neck down. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur. |
| Included Components | Shampoo |
| Item Package Dimensions L x W x H | 6.02 x 2.64 x 1.97 inches |
| Item Weight | 8.8 ounces |
| Item model number | D98110P |
| Item model number | D98110P |
| Liquid Volume | 6.7 Fluid Ounces |
| Manufacturer | Douxo S3 |
| Manufacturer | Douxo S3 |
| Material | Liquid |
| Model Name | DOUXO® S3 CALM Shampoo 6.7 oz (200 mL) |
| Number of Items | 1 |
| Package Dimensions | 6.02 x 2.64 x 1.97 inches; 8.78 ounces |
| Pet Type | Cat, Dog |
| Size | 6.7 oz |
| Special Ingredients | Ophytrium |
| Specific Uses for Product | allergy-relief |
| Target Audience Keyword | Cats, Dogs, dogs |
| Target Species | dog, cat |
| UPC | 850002593389 |
M**A
Excellent relief for itchy, sensitive skin
I bought this shampoo for my dog who suffers from allergies, itching, and irritated skin, especially around the ears. After just a few washes, I noticed a big improvement. The redness and itching were reduced, and my dog seemed much more comfortable. The shampoo is very gentle, has a light scent, and lathers well. It doesn’t dry out the skin and leaves the coat soft and clean. I also like that it’s recommended by veterinarians and contains Ophytrium, which really seems to help calm the skin. If your dog has sensitive skin, allergies, or frequent itching, this shampoo is definitely worth it. I will continue using it and highly recommend it.
A**R
Perfect for dogs with skin issues
My dog has skin issues. This soap has saved us. The only soap that leaves his fur smelling and feeling great. Has helped stop his itching. Perfect skin care for dogs with skin issues.
S**E
Must have four dogs with skin irritation
This shampoo does a great job of cleaning my Rotty. Her fur is super soft and smells great. It seems to really help her dry skin as well. The directions are super simple and the pump makes it easy to follow. Best part is being $50 less than the vet wanted.
P**U
A great shampoo product for dogs and cats who have itchy. Irritated skin. Worth the money
DouxoS3, calm dogs or cats shampoo with OPHYTRIUM 0.75 for itchy, irritated skin. This shampoo has worked for my three little dogs. It is labeled "A SAFE SKINCARE SOLUTION" Soap, Sulfate and parables free. It has an easy pump top for dispensing, no medicated odor to this shampoo. Great lather, feels very soothing. Safe for small and large dogs and cats. It's nice to see them not feeling itchy or irritated. No more skin scratching. This is a good product in my opinion with no harsh unsafe chemicals. Your dog or cat will thank you for it!!
S**T
Answered prayers!
This shampoo is amazing!! I have a golden who is an itchy boy, but most especially after baths no matter the shampoo we used. We tried sensitive shampoos, oatmeal, and medicated shampoos and treatments but they all made him super itchy. So much so that I would need to take him to the vet for a cytopoint shot because he would be in itchy agony, sometimes itching his skin raw. But this shampoo has been an answer to my prayers! He hasn’t itched at all and his fur has stayed clean and soft for much longer than usual. If you have an itchy dog just give it a try!
J**.
Really Good product
I think this is a good product too, this company's calm spray is so amazing that it is hard to know if the shampoo helped but, it smells good and provided a good rich lather which is needed for a long hair dog. Below is the review that I wrote for their calm spray: This is the most amazing product I have ever used on my Dog. My dog has had skin issues for a couple years. Bacteria, yeast, ear, belly, groin area skin issues. We have used lots of vet reccomended products for these issues. . Our dog is a Bohemian Shepherd from the Czech Republic, he is like a small long haired German Shepherd. This breed is used to a very cold place. Currently it is winter and we have radiant heated floors. He does not like that and he get dry scabby skin all over his belly and under his under arms (front legs). We tried MiconaHex + Triz and some spray from the pet store. They didn't do squat but, this Douxo spray is freaking MAGIC - TOTTALLY UNBELIEVABLY FANTASTIC. I saw a huge difference after only 2 applications and after 4 the problem is gone !!!!!!!!!!!!!! I rarely write a great review because most products are garbage. WELL DON DOUXO
A**N
A Lifesaver for My Dog’s Skin — Worth Every Penny
I’ve tried a lot of products to manage my dog’s skin issues, but Douxo S3 Calm is the only shampoo that’s consistently helped. My golden retriever, Luna, has a dust mite allergy and a history of sensitive skin and occasional staph infections, especially when staying in dusty or older environments. This shampoo has become part of our routine, and it’s made a real difference. It’s gentle, fragrance-free, and doesn’t dry her out — even with more frequent use. Her skin looks calmer, less red, and she scratches way less after a bath. I’ve noticed fewer flare-ups since switching to this and sticking to a consistent bathing schedule. If your dog has allergy-prone or reactive skin like mine, this is the one to try. It’s pricey, but it actually works — and that’s what matters.
R**N
Determologist approved, and worked well
This stuff worked wonders on my itchy puppy. It really soothed her skin and gave her comfort. This stuff worked really well. The determologist said that is the best thing to use other that medicated shampoo from the vet.
J**S
Works well
E**G
At first few use, it doesn’t seem to do much. But after repeated use for 3 months, can sense the dog skin slightly improving. It is not as effective as Malaseb (another brand), but it is less drying than that.
S**O
Help with dog itching
Trustpilot
2 weeks ago
5 days ago